Senior Manager, R&D

About this job

Join us as a strategic R&D team lead within Chemical Synthesis Solutions (CSS) R&D at MilliporeSigma. In this pivotal role, you will serve as the cornerstone scientific bridge between chemistry and biology. You are a dual-domain expert: a chemist with deep protein/peptide/DEL and medicinal chemistry foundations who independently designs and executes the in vitro biochemical and cell-based assays required to validate chemical hypotheses. Your work spans the full early drug discovery continuum — from target identification and mechanism of action (MOA) studies, through proof-of-concept (PoC) validation of CSS chemical products and proprietary platforms, to enabling the characterization of novel therapeutic modalities including peptide drugs, ADCs, ASOs, and targeted protein degraders.…

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