Senior Scientist, siRNA Design and Off-Target Analysis
AbbVie · Worcester
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- Company
- AbbVie
- Location
- Worcester
- Employment type
- Full-time
- Posted
- August 17, 2026
About this job
AbbVie's Biotherapeutic and Genetic Medicine (BGM) department is seeking a highly motivated Senior Scientist with deep expertise in computational biology, molecular design, and next-generation sequencing to support siRNA design and off-target assessment. This role will establish and optimize siRNA sequences with enhanced knockdown efficacy and reduced off-target liabilities, develop off-target assessment workflows, and integrate transcriptomic and genomic data. The ideal candidate will combine strong biological insight with quantitative skills to advance siRNA design, identify potential off-target risks, and contribute to the development of safer, more selective RNA-based therapeutics.…
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